深圳欣博盛生物科技有限公司 a1

货号:GTX11610 规格:25μg 目录价:¥6600
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MMP11 antibody
别名:
matrix metallopeptidase 11 , SL-3 , ST3 , STMY3
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA, IHC, IP, WB
靶标/特异性:
Reacts with reduced and non-reduced MMP-11. Recognizes the pro-form of MMP-11 at 58 kDa but not the active form at 45 kDa.
同种型:
IgG
免疫原:
Synthetic peptide (Human) Propeptide.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
~1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
预期分子量:
55
产品形式:
Liquid
存储溶液:
PBS, 50% Glycerol, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1 proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
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