MMP2 antibody-多抗-深圳欣博盛生物科技有限公司

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MMP2 antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX25704

规格：50μg

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

MMP2 antibody

别名:

matrix metallopeptidase 2 , CLG4 , CLG4A , MMP-2 , MMP-II , MONA , TBE-1

反应种属:

Bovine, Dog, Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

ELISA, IP, WB

靶标/特异性:

This antibody is specific to MMP2, and does not cross react with MMP1, 3, 7, 8, 9, 10 or 16.

同种型:

IgG

免疫原:

Synthetic peptide corresponding to C-terminus of MMP2 (Human).

克隆性:

Polyclonal

克隆号:

纯化方式:

Immunogen affinity purified

偶联:

Unconjugated

产品浓度:

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.05% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]

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