MMP9 Antibody: HRP-单抗-深圳欣博盛生物科技有限公司

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MMP9 Antibody: HRP

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SMC-396D-HRP

规格：100 µg

目录价：￥4750.2

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

MMP9 Antibody: HRP

别名:

MMP-9 Antibody, CLG4B Antibody, 82kDa matrix metalloproteinase-9 Antibody, collagenease type 4 beta Antibody, GELB Antibody, Macrophage gelatinase Antibody, MANDP2 Antibody, Type V collagenase Antibody, 92 kDa gelatinase Antibody, 92 kDa type IV collagenase Antibody, Gelatinase B Antibody, MMP9 Antibody, Matrix metalloproteinase 9 Antibody

产品描述:

Mouse Anti-Rat MMP9 Monoclonal IgG2a

反应种属:

Human | Mouse | Rat

宿主来源:

Mouse

实验应用:

WB | IHC | ICC/IF | IP | FCM

靶标/特异性:

Detecs ~92kDa and ~82kDa (pro and active forms).

同种型:

IgG2a

推荐稀释度:

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

免疫原:

Fusion protein amino acids 1-708 (full length) of rat MMP9

免疫原种属:

Rat

克隆性:

Monoclonal

克隆号:

L51/82 (Formerly sold as S51-82)

纯化方式:

Protein G Purified

偶联:

HRP

产品浓度:

1 mg/ml

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

MMP9, otherwise known as matrix metalloproteinase 9, is involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction and tissue remodeling, as well as in disease processes like arthritis and metastasis (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (5).

Accession #:

NP_112317.1