Mononucleosomes (H2AX), Human Recombinant Biotinylated-突变/修饰核小体-深圳欣博盛生物科技有限公司

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Mononucleosomes (H2AX), Human Recombinant Biotinylated

品牌：EpiCypher

官网链接

说明书

折扣/货期

货号：16-0013

规格：50 µg

目录价：￥5700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Mononucleosomes (H2AX), Human Recombinant Biotinylated

产品描述:

Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2AX, H2B, H3 and H4. Accession numbers: H2AX-P16104; H2B-O60814; H3.1-P68431; H4-P62805) wrapped by 147 base pairs of 601 positioning sequence DNA with a 5’ biotin-TEG group. The nucleosome is the basic subunit of chromatin. H2AX is a variant of histone H2A that is phosphorylated on serine 139 by the ATM and ATR kinases in response to DNA double strand breakage. Phosphorylation of H2AX serves to recruit a number of DNA damage repair proteins, such as BRCA1 and NBS1.

保存温度:

Stable for six (6) months at -80°C from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.

运输温度:

Dry ice.

产品形式:

Purified recombinant mononucleosomes (50 µg total mass, 27.4 µg in 50.0 µL) in 10 mM Tris-HCl pH 7.5, 1 mM EDTA, 25 mM NaCl, 2 mM DTT, & 20% glycerol. Concentration of nucleosomes is 4.94 µM. Nucleosome molecular weight = 202,308.2 Da.

产地:

美国

生产商:

EpiCypher

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