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折扣/货期| 货号：GTX04319-pro | 规格：10μg | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Mouse TGF beta 1 protein, His tag (active)
实验应用:
Functional Assay, Neutralizing /Inhibition, WB
克隆号:
偶联:
Unconjugated
产品浓度:
表达系统:
E. coli
保存温度:
Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
运输温度:
4°C
产品形式:
Lyophilized powder
存储溶液:
Reconstitute in 20mM Tris, 150mM NaCl pH8.0 to a concentration of 0.1-1.0 mg/mL. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl pH8.0, 0.05% sarcosyl, 5% trehalose, 5% Proclin300.
生产商:
GeneTex
功能与背景:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. Mice lacking a functional copy of this gene develop severe multifocal inflammatory disease, yolk sac defects and colon cancer. [provided by RefSeq, Aug 2016]
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