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折扣/货期| 货号：GTX23370 | 规格：250μl | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MRP1 antibody [QCRL3]
别名:
ATP binding cassette subfamily C member 1 , ABC29 , ABCC , GS-X , MRP , MRP1
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC
靶标/特异性:
This antibody detects a 190 kDa transmembrane phosphoglycoprotein overexpressed in various hummation dependent multidrug resistant tumor cell lines. It does not cross react with human MDR1 and MDR3, or mouse MRP gene products.
同种型:
IgG2a
免疫原:
Membranes prepared from the human small cell lung cancer cell line H69AR which highly overexpresses MRP
克隆性:
Monoclonal
克隆号:
QCRL3
纯化方式:
IgG fraction
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
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