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折扣/货期| 货号：GTX01885 | 规格：500μl | 目录价：￥8000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MSH6 antibody [PU29]
别名:
mutS homolog 6 , GTBP , GTMBP , HNPCC5 , HSAP , p160
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
同种型:
IgG1
免疫原:
Prokaryotic recombinant protein corresponding to a 359 amino acid portion of the MSH6 human molecule.
克隆性:
Monoclonal
克隆号:
PU29
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Tissue culture supernatant, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
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