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折扣/货期| 货号：V7430SAF-100UG | 规格：100 ug | 目录价：￥6652.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MSH6 Antibody
产品描述:
MSH6 is a component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. [UniProt]
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB, IHC-P, FACS
同种型:
Mouse IgG2b, kappa
免疫原:
A portion of amino acids 374-540 from the human protein were used as the immunogen for this MSH6 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
MTS6-1
纯化方式:
Protein G affinity chromatography
保存温度:
Store the MSH6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
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