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折扣/货期| 货号：V5800-100UG | 规格：100 ug | 目录价：￥6652.1 |
| 货号：V5800-20UG | 规格：20 ug | 目录价：￥3082.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
mtTFA Antibody | Mitochondrial transcription factor 1 / TFAM
产品描述:
mtTFA (mitochondrial transcription factor A), also known as mtTF1, TFAM, TCF6 (for transcription factor 6-like1), TCF6L2 and tsHMG, is a nuclear-encoded gene product that is imported into the mitochondria. mtTFA is required for many aspects of mitochondrial biogenesis including the replication and transcription of mitochondrial DNA (mtDNA). In mouse, testis-specific mtTFA is missing the mitochondria targeting sequence and is present in the nucleus rather than the mitochondria. This form of mtTFA is located primarily in the nuclei of elongated spermatids and may be involved in the regulation of gene expression of the haploid male genome. During mouse and human spermatogenesis there is a reduction of mtTFA protein levels and a reduction in mtDNA copy number. These features may provide one of the mechanisms by which paternal mtDNA transmission is prevented. mtTFA has been associated with mitochondrial disorder in humans characterized by ocular myopathy, exercise intolerance and muscle wasting.
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P, WB
同种型:
Mouse IgG, kappa
免疫原:
A portion of amino acids 1-200 from human Mitochondrial transcription factor 1 protein was used as the immunogen for the mtTFA antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
TFAM/9713
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the mtTFA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
上一个:Recombinant BRAF V600E Antibody
下一个:mtTFA Antibody | Mitochondrial transcription factor 1 / TFAM
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