| 货号:V5799SAF-100UG | 规格:100 ug | 目录价:¥6652.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Recombinant BRAF V600E Antibody
产品描述:
The BRAF gene encodes a protein that is part of the RAS-RAF-MEK-ERK signaling pathway, which regulates cell division and proliferation. The V600E mutation in the BRAF gene leads to the production of a constitutively active BRAF protein, resulting in uncontrolled cell growth and division. Identifying the presence of this mutation is crucial for diagnosing and guiding the treatment of certain cancers. The BRAF (V600E) antibody is used in immunohistochemistry to detect the presence of a specific mutation in the BRAF gene known as V600E. This mutation is commonly associated with various cancers, including melanoma, colorectal cancer, and certain types of thyroid cancer, lung cancer, and Hairy cell leukemia. The BRAF (V600E) antibody specifically binds to the mutated BRAF protein, allowing pathologists to detect the mutation in cancer tissue. Immunohistochemistry using this antibody is often employed in the evaluation of tumor specimens to aid in the diagnosis and classification of cancers.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
同种型:
Rabbit IgG, kappa
免疫原:
A recombinant fragment specific to human BRAF V600E mutant protein was used as the immunogen for the recombinant BRAF V600E antibody.
克隆性:
Recombinant Rabbit Monoclonal
克隆号:
BRAF-V600E/13276R
纯化方式:
Protein A affinity
保存温度:
Aliquot the recombinant BRAF V600E antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
上一个:Recombinant BRAF V600E Antibody
下一个:mtTFA Antibody | Mitochondrial transcription factor 1 / TFAM
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