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折扣/货期| 货号：GTX34856 | 规格：100μg | 目录价：￥7000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MUC1 antibody [SPM132]
别名:
ADMCKD , ADMCKD1 , CA 153 , CD227 , EMA , H23AG , KL6 , MAM6 , MCD , MCKD , MCKD1 , MUC1 , MUC1/SEC , MUC1/X , MUC1/ZD , PEM , PEMT , PUM , mucin 1, cell surface associated , Mucin1 , CA15-3 , CA15.3
反应种属:
Human
宿主来源:
Mouse
实验应用:
FCM, ICC/IF, IHC-P
靶标/特异性:
In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA. This MAb reacts with the DTRP epitope in the tandem repeats.
同种型:
IgG1
免疫原:
Human milk fat globule membranes
克隆性:
Monoclonal
克隆号:
SPM132
纯化方式:
Protein A/G purified
偶联:
Unconjugated
产品浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
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