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折扣/货期| 货号：GTX639940 | 规格：100μg | 目录价：￥6500 |
| 货号：GTX639940-S | 规格：50μg | 目录价：￥3300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MX1 antibody [HMV316] HistoMAX™
别名:
phosphoribosyl transferase domain containing 1 , HHGP
反应种属:
Human, Rat
宿主来源:
Rabbit
实验应用:
ELISA, WB
同种型:
IgG
免疫原:
PRTFDC1 antibody was raised against a 14 amino acid synthetic peptide from near the center of human PRTFDC1.The immunogen is located within amino acids 90 - 140 of PRTFDC1.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
26
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.
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