Mycobacterium bovis BCG Recombinant HSP65 Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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Mycobacterium bovis BCG Recombinant HSP65 Protein

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPR-116B

规格：100 µg

目录价：￥4384.8

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Mycobacterium bovis BCG Recombinant HSP65 Protein

别名:

60kDa chaperonin 2 Protein, Antigen A Protein, Cell wall protein A Protein, groEL Protein, GroEL2 Protein, GroL2 Protein, M. Tuberculosis cell wall protein A Protein, M. Tuberculosis HSP65 Protein, Protein Cpm60 2 Protein

产品描述:

Mycobacterium bovis BCG Recombinant HSP65 Protein

反应种属:

Mycobacterium bovis BCG

实验应用:

WB | SDS-PAGE | Functional Assay | ELISA

纯化方式:

Multi-Step Purified

偶联:

No tag

产品浓度:

Lot/batch specific. See included datasheet.

表达系统:

E. coli

保存温度:

-20ºC

运输温度:

Blue Ice or 4ºC

预期分子量:

~65 kDa

存储溶液:

20mM Tris/HCl, pH 7.5, 0.45M NaCl, 10% glycerol, 5mM bMe

产地:

加拿大

功能与背景:

HSP65 isolated from Mycobacterium bovis BCG, is a member of the HSP60 family of heat shock proteins (2, 3). HSP60s are mitochondrial chaperonins that are typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. In addition to its role as a heat shock protein, HSP60 functions as a chaperonin to assist in folding linear amino acid chains into their respective three-dimensional structure. HSP60s are a ubiquitous class of HSPs that specifically promote the folding and assembly of cellular polypeptides in an ATP-dependent manner (1). Specifically, sequence comparison of HSP65 from different mycobacterium strains showed that the protein sequence of M. bovis BCG is identical to that of M. tuberculosis, and very similar to that of M. leprae, the pathogens that cause tuberculosis and tuberculoid leprosy, respectively (2,4). Mycobacterium bovis BCG HSP65 was identified as the immunodominant antigen during mycobacterial diseases and vaccination. It is also believed to be the antigen that induces autoimmune disease, such as adjuvant arthritis in rats (5, 6).

纯度:

>90%

Accession #:

M17705.1

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