| 货号:GTX31543 | 规格:100μg | 目录价:¥6200 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
N-RAS antibody
别名:
NRAS proto-oncogene, GTPase , ALPS4 , CMNS , N-ras , NCMS , NRAS1 , NS6
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ELISA, WB
靶标/特异性:
N-RAS antibody is predicted to not cross-react with H-RAS
同种型:
IgG
免疫原:
N-RAS antibody was raised against a 15 amino acid peptide near the carboxy terminus of human N-RAS. The immunogen corresponding to a region within amino acids 139 and 189 of human N-RAS
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
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