NARF antibody [N3C2], Internal-多抗-深圳欣博盛生物科技有限公司

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NARF antibody [N3C2], Internal

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX115821-S	规格：25μl	目录价：￥1700
货号：GTX115821	规格：100μl	目录价：￥4000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

NARF antibody [N3C2], Internal

别名:

nuclear prelamin A recognition factor , IOP2

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

ICC/IF, IHC-P, WB

同种型:

IgG

免疫原:

Recombinant protein encompassing a sequence within the center region of human NARF. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.

生产商:

GeneTex

功能与背景:

Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing. [provided by RefSeq]

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