NFYA antibody-多抗-深圳欣博盛生物科技有限公司

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NFYA antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX48667

规格：50μl

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

NFYA antibody

别名:

nuclear transcription factor Y subunit alpha , CBF-A , CBF-B , HAP2 , NF-YA

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ELISA, EMSA, IHC-P, WB

同种型:

IgG

免疫原:

NF-Y (A subunit specific) peptide corresponding to a region near the N-terminus of the human protein conjugated to KLH.

克隆性:

Polyclonal

克隆号:

纯化方式:

Unpurified

偶联:

Unconjugated

产品浓度:

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

Filtered-steriled serum, 0.01% Sodium azide.

生产商:

GeneTex

功能与背景:

Nuclear transcription factor Y subunit alpha is a protein that in humans is encoded by the NFYA gene. The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. Anti-NF-Y is ideal for investigators involved in transcription factor research.

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