NIPBL antibody, Internal-多抗-深圳欣博盛生物科技有限公司

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NIPBL antibody, Internal

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX88110

规格：100μg

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

NIPBL antibody, Internal

别名:

NIPBL cohesin loading factor , CDLS , CDLS1 , IDN3 , IDN3-B , Scc2

反应种属:

Human

宿主来源:

Goat

实验应用:

ICC/IF, IHC-P

靶标/特异性:

This antibody is expected to recognize both reported isoforms (NP_597677.2; NP_056199.2).

同种型:

IgG

免疫原:

Peptide with sequence C-RPDSPRVKQGDSNK, from the internal region of the protein sequence according to NP_597677.2; NP_056199.2.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

偶联:

Unconjugated

产品浓度:

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

TBS, 0.5% BSA, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and cognitive disability. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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