官网链接
折扣/货期| 货号：GTX50221 | 规格：100μl | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
NMDAR2B (phospho Tyr1472) antibody
别名:
glutamate ionotropic receptor NMDA type subunit 2B , EIEE27 , GluN2B , MRD6 , NMDAR2B , NR2B , NR3 , hNR3
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ICC/IF, WB
靶标/特异性:
This antibody is raised against phopsho peptide of human NMDAR2B Tyr1474, which shares 100% identity identity with rat NMDAR2B around Tyr1472.
同种型:
IgG
免疫原:
Peptide sequence around phosphorylation site of Tyr1474 (H-V-Y(p)-E-K) derived from human NMDAR2B.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia. [provided by RefSeq, Aug 2017]
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