NPR-A antibody-多抗-深圳欣博盛生物科技有限公司

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NPR-A antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX14918

规格：100μg

目录价：￥6400

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

NPR-A antibody

别名:

natriuretic peptide receptor 1 , ANPRA , ANPa , GUC2A , GUCY2A , NPRA

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

ELISA, ICC/IF, IHC, IHC-Wm, IP, WB

靶标/特异性:

The selective antibodies were generated against conserved sequences near the N terminus and the C terminal end of the protein that are unique to PGCA protein. The PGCA antibody labels a 127 to 130 kDa protein in various tissues.

同种型:

IgG

免疫原:

Synthetic peptide corresponding to C terminal amino acids 1042-1057 of Human NPR-A protein. Seqence: VRTYWLLGERGCSTRG

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

0.85 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

Tris/Glycine, 0.5% BSA, 30% Glycerol, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).[supplied by OMIM, May 2009]

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