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折扣/货期| 货号：GTX83995 | 规格：100μl | 目录价：￥7300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
NSE2 antibody [6A6]
别名:
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase , C8orf36 , MMS21 , NSE2 , ZMIZ7
反应种属:
Human
宿主来源:
Mouse
实验应用:
FCM, ICC/IF, WB
同种型:
IgG2a
免疫原:
Full length human recombinant protein of human NSMCE2 (NP_775956) produced in E.coli.
克隆性:
Monoclonal
克隆号:
6A6
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
0.52 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.
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