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折扣/货期| 货号：GTX85185 | 规格：100μg | 目录价：￥6200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
NSE2 antibody
别名:
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase , C8orf36 , MMS21 , NSE2 , ZMIZ7
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ELISA, WB
同种型:
IgG
免疫原:
MMS21 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human MMS21.The immunogen is located within amino acids 170 - 220 of MMS21.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
28
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.
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