NUCB2 (mouse) (rec.) (His)-其他重组蛋白-深圳欣博盛生物科技有限公司

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NUCB2 (mouse) (rec.) (His)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40A-0074-C010	规格：10 ug	目录价：￥2040
货号：AG-40A-0074-C050	规格：50 ug	目录价：￥4320

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

NUCB2 (mouse) (rec.) (His)

别名:

DNA-binding Protein NEFA; Prepronesfatin; Nucb2; Nesfatin

产品描述:

Nucleobindin-2 (NUCB2; Prepronesfatin) was first isolated in adipocytes, but is also expressed by gastric mucosa and pancreatic beta cells. This pattern of nucleobindin-2 expression, as well as the presence of nucleobindin-2 within the plasma of rodents and humans, strongly suggests that this compound may act as a circulating regulatory factor. NUCB2 can be cleaved into three polypeptides: nesfatin-1, nesfatin-2, and nesfatin-3. Anorexigenic effects have been described for nesfatin-1 that plays an important role in hypothalamic pathways regulating food intake and energy homeostasis and acting in a leptin-independent manner. Nesfatin-1 may also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance. Nucleobindin-2 is therefore reported to reduce food intake after administration, mostly refering to the cleaved peptide nesfatin-1. Excess nucleobindin-2/nesfatin-1 in the brain leads to a loss of appetite, lack of the protein in the brain leads to an increase of appetite.

宿主来源:

E. coli

保存温度:

+4°C

运输温度:

预期分子量:

~55kDa (SDS-PAGE)

产品形式:

liquid

存储溶液:

Liquid. 0.2µm-filtered solution in PBS, pH 7.2.

产地: