Oncogenic Mutant H3.3G34R Recombinant Nucleosome, Biotinylated-突变/修饰核小体-深圳欣博盛生物科技有限公司

首页产品中心突变/修饰核小体

Oncogenic Mutant H3.3G34R Recombinant Nucleosome, Biotinylated

品牌：EpiCypher

官网链接

说明书

折扣/货期

货号：16-0346

规格：50 µg

目录价：￥5700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Oncogenic Mutant H3.3G34R Recombinant Nucleosome, Biotinylated

产品描述:

H3.3 is a histone variant found in regions of high chromatin turnover outside of S-phase (e.g., at actively transcribed genes). The substitution of R for G at position 34 of H3.3 interferes with SETD2-mediated H3K36 methylation. This mutation has been associated with bone cancers and astrocytomas [1]. Oncogenic Mutant H3.3G34R Recombinant Nucleosome, Biotinylated consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of H2A, H2B, H3.3G34R, and H4) to form a nucleosome, the basic repeating unit of chromatin. The 147 bp 601 sequence, identified by Lowary and Widom [2], has high affinity for histone octamers and is useful for nucleosome assembly. The DNA contains a 5’ biotin-TEG group.

宿主来源:

Human

表达系统:

E. coli & synthetic DNA

保存温度:

Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws.

运输温度:

Dry ice.

产地:

美国

生产商:

EpiCypher