ORP150 antibody [C2C3], C-term-多抗-深圳欣博盛生物科技有限公司

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ORP150 antibody [C2C3], C-term

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX102255	规格：100μl	目录价：￥4000
货号：GTX102255-S	规格：25μl	目录价：￥1700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

ORP150 antibody [C2C3], C-term

别名:

hypoxia up-regulated 1 , GRP-170 , Grp170 , HSP12A , IMD59 , ORP-150 , ORP150

反应种属:

Human, Mouse, Plant, Rat

宿主来源:

Rabbit

实验应用:

ICC/IF, IHC-P, WB

同种型:

IgG

免疫原:

Recombinant protein encompassing a sequence within the C-terminus region of human ORP150. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

0.27 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. [provided by RefSeq]

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