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折扣/货期| 货号：GTX11503 | 规格：25μg | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Osteopontin antibody
别名:
secreted phosphoprotein 1 , 2AR , Apl-1 , BNSP , BSPI , Bsp , ETA-1 , Eta , OP , Opn , Opnl , Ric , Spp-1
反应种属:
Mouse
宿主来源:
Goat
实验应用:
ELISA, IHC, Neutralizing/Inhibition, WB
同种型:
IgG
免疫原:
purified recombinant mouse osteopontin expressed in NSO cells.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
32
产品形式:
Liquid
存储溶液:
PBS, 5% Trehalose, no preservatives.
生产商:
GeneTex
功能与背景:
Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. OPN is multifunctional, with activities in cell migration, cell survival, inhibition of calcification, regulation of immune cell function, and control of tumor cell phenotype. Targeting of the gene encoding Osteopontin, has revealed that while it is not necessary for normal embryonic development, fertility, and health under pathogen-free conditions, loss of the protein has significant consequences in several models of injury/disease as diverse as renal injury, viral and bacterial infection, bone remodeling, and tumor growth. The fact that no other proteins seem to share a redundant activity with Osteopontin under these conditions suggests that it has a unique functional role during tissue injury and stress.
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