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折扣/货期| 货号：GTX12222 | 规格：50μg | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
P-Cadherin antibody [NCC-CAD-299]
别名:
CDH3 , CDHP , HJMD , PCAD , cadherin 3 , P-Cadherin , Cadherin 3
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-Fr, Neutralizing /Inhibition, WB
靶标/特异性:
This antibody inhibits P- Cadherin dependent cell-cell contact.
同种型:
IgG1
免疫原:
Human epidermal carcinoma cell line A431.
克隆性:
Monoclonal
克隆号:
NCC-CAD-299
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]
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