官网链接
折扣/货期| 货号：GTX14975 | 规格：50μg | 目录价：￥7000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
p21 Cip1 antibody
别名:
CAP20 , CDKN1 , CDKN1A , CIP1 , MDA6 , P21 , SDI1 , WAF1 , cyclin dependent kinase inhibitor 1A , p21CIP1 , p21 , p21 Cip1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
Synthetic peptide corresponding to aa139-64 of the p21 protein.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
18
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Sep 2015]
您可能感兴趣的产品
WDR24 antibody
货号：GTX133576
Avian Influenza A virus H9N2 HA (Hemagglutinin) antibody
货号：GTX127306
Influenza A virus M2 (matrix protein) antibody
货号：GTX125951
Acta2 antibody
货号：GTX124505
MCTS1 antibody [N1C3]
货号：GTX117793
MAFG antibody
货号：GTX114541
Golgin 97 antibody [C2C3], C-term
货号：GTX114445
Aconitase 2 antibody [N1N3]
货号：GTX114233
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询