官网链接
折扣/货期| 货号：GTX639569 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX639569-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
p38 MAPK (phospho Tyr182) antibody [HL2740]
别名:
mitogen-activated protein kinase 14 , CSBP , CSBP1 , CSBP2 , CSPB1 , EXIP , Mxi2 , PRKM14 , PRKM15 , RK , SAPK2A , p38 , p38ALPHA
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P, WB
靶标/特异性:
This antibody detects p38 MAPK protein when singly phosphorylated at Tyr182 but does not recognize p38 MAPK protein when singly phosphorylated at Tyr180 or dually phosphorylated at Tyr180 and Tyr182.
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide surrounding phospho Tyr182 of human p38 MAPK. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL2740
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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