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折扣/货期| 货号：GTX30768 | 规格：50μl | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
p53 (acetyl Lys373) antibody
别名:
BCC7 , LFS1 , P53 , TP53 , TRP53 , tumor protein p53 , p53
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IP, WB
靶标/特异性:
Specific for human p53 acetylated in vitro by recombinant p300, and for peptide containing acetyllysine 373 but not for the peptide containing acetyllysine 320. Modest crossreactivity for p53 acetylated in vitro by recombinant PCAF.
同种型:
IgG
免疫原:
KLH-conjugated, synthetic peptide corresponding to aa367-379 of human p53 (SHLKSK[AcK]GQSTSR, where AcK denotes acetyllysine). The specificity was demonstrated with synthetic acetylated peptides.
克隆性:
Polyclonal
克隆号:
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
44
产品形式:
Liquid
存储溶液:
Serum, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
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