| 货号:GTX22506 | 规格:100μg | 目录价:¥5300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
p63 antibody
别名:
AIS,B(p51A),B(p51B),EEC3,KET,LMS,NBP,OFC8,RHS,SHFM4,TP53CP,TP53L,TP63,TP73L,p40,p51,p53CP,p63,p73H,p73L,tumor protein p63
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
ELISA, IHC, WB
靶标/特异性:
This antibody is specific for p51A. It does not cross react with p51B
同种型:
IgG
免疫原:
Synthetic peptide C-423EPRRETPKQSDVFFRHSKPPNRS445 corresponding to C-terminal of human p51A
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
77
产品形式:
Liquid
存储溶液:
10mM KHPO₄, 140mM NaCl, 0.1% BSA, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016]
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