官网链接
折扣/货期| 货号：GTX46123 | 规格：100μl | 目录价：￥6600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
p73 antibody [5B429]
别名:
tumor protein p73 , P73
反应种属:
Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
ChIP assay, FCM, ICC/IF, IHC-Fr, IHC-P, IP, MS, WB
靶标/特异性:
p73 antibody (clone 5B429) recognizes all of the TAp73 isoforms i.e. isoforms with an intact NH2-terminal transactivation domain (Thottassery et el, 2006, PMID 16505115). Sayan et al 2005 (PMID 15781249) showed that p73 antibody (clone 5B429) reacted with all tested TAp73 isoforms but not deltaNp73 whereas p73 antibody clone 5B1288 showed reactivity against all p73 isoforms including delta Np73. Caspase-cleaved p73 fragments, including 55 kDa and 45 kDa, have been described in literature (Sayan et al, 2008). p73 antibody clone 5B429 has also been referred to as 429 in the literature.
同种型:
IgG1
免疫原:
This antibody was raised against full-length human p73. It reacts with an epitope that is located on the N-terminal region of human p73. It does not cross react with p53.
克隆性:
Monoclonal
克隆号:
5B429
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
70
产品形式:
Liquid
存储溶液:
PBS, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes tumor protein p73, which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73 and have high sequence similarity to one another, which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways involving direct or indirect protein interactions, resulting in regulation of the same target gene promoters or regulation of each other's promoters. The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors. The p73 gene expresses at least 35 mRNA variants due to the use of alternate promoters, alternate translation initiation sites, and multiple splice variations. Theoretically this can account for 29 different p73 isoforms; however, the biological validity and the full-length nature of most variants have not been determined. [provided by RefSeq]
您可能感兴趣的产品
VSV-G-Tag Monoclonal Antibody
货号：ORF.VSVGMAB-50
T7-Tag Monoclonal Antibody
货号：ORF.T7MAB-50
Myc-Tag Monoclonal Antibody
货号：ORF.MYCMAB-50
His-Tag Monoclonal Antibody
货号：ORF.HISMAB-50
HA-Tag Monoclonal Antibody
货号：ORF.HAMAB-50
GST-Tag Monoclonal Antibody
货号：ORF.GSTMAB-50
GFP-Tag Monoclonal Antibody
货号：ORF.GFPMAB-50
Flag-Tag Monoclonal Antibody
货号：ORF.FLAGMAB-50
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询