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折扣/货期| 货号：GTX10195 | 规格：100μg | 目录价：￥4300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PAPP A antibody [10H9]
别名:
pappalysin 1 , ASBABP2 , DIPLA1 , IGFBP-4ase , PAPA , PAPP-A , PAPPA1
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, IP
靶标/特异性:
This antibody is specific to PAPP A subunit of the heterotetrameric complex of PAPP-A (htPAPP-A). It can be used to detect htPAPP-A (when paired with another antibody specific for proMBP) or PAPP-A dimer (when paired with another antibody specific for PAPP A subunit)
同种型:
IgG2a
免疫原:
Purified human PAPP-A/proMBP (heterotetrameric PAPP-A, htPAPP-A) complex.
克隆性:
Monoclonal
克隆号:
10H9
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017]
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