| 货号:RQ7624 | 规格:100 ug | 目录价:¥6488 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Parkinson disease protein 7 Antibody / PARK7
产品描述:
Parkinson disease (autosomal recessive, early onset) 7, also known as DJ1, is a protein which in humans is encoded by the PARK7 gene. PARK7 belongs to the peptidase C56 family of proteins. PARK7 is mapped to chromosome 1p36. It acts as a positive regulator of androgen receptor-dependent transcription. It is also involved in tumorigenesis and in maintaining mitochondrial homeostasis. This gene may also function as a redox-sensitive chaperone, as a sensor foroxidative stress, and it apparently protects neurons against oxidative stress and cell death. It has been found that PARK7 mutations that impair transcriptional coactivator function can render dopaminergic neurons vulnerable to apoptosis and may contribute to the pathogenesis of Parkinson disease.
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB, IHC-P, IF, FACS
同种型:
Mouse IgG2b
免疫原:
E. coli-derived recombinant human protein (amino acids A2-D189) was used as the immunogen for the Parkinson disease protein 7 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
4B10
纯化方式:
Antigen affinity purified
保存温度:
After reconstitution, the Parkinson disease protein 7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
促销活动
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