PAX5 antibody-多抗-深圳欣博盛生物科技有限公司

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PAX5 antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX54532

规格：100μg

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PAX5 antibody

别名:

paired box 5 , ALL3 , BSAP

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

FCM, ICC/IF, IHC-P, IP, WB

同种型:

IgG

免疫原:

Purified internal fragment of human recombinant PAX5 expressed in E. coli

克隆性:

Polyclonal

克隆号:

纯化方式:

Protein G purified

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.1% BSA, 30% Glycerol, 0.05% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

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