PC1/3 antibody-多抗-深圳欣博盛生物科技有限公司

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PC1/3 antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX11786

规格：50μl

目录价：￥6600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PC1/3 antibody

别名:

proprotein convertase subtilisin/kexin type 1 , BMIQ12 , NEC1 , PC1 , PC3 , SPC3

反应种属:

Human, Monkey, Rat

宿主来源:

Rabbit

实验应用:

同种型:

IgG

克隆性:

Polyclonal

克隆号:

纯化方式:

Serum

偶联:

Unconjugated

产品浓度:

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

Serum, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. The protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene [provided by RefSeq, Jan 2014]

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