PD-1 (human) ELISA Kit-人ELISA试剂盒-深圳欣博盛生物科技有限公司

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PD-1 (human) ELISA Kit

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-45B-0015-KI01

规格：96 wells

目录价：￥7320

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PD-1 (human) ELISA Kit

别名:

CD279; Programmed Cell Death Protein 1

产品描述:

PD-1 (Programmed Cell Death Protein 1; CD279) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4 family have been shown to either promote T cell activation (CD28 and ICOS) or downregulate T cell activation (CTLA-4 and PD-1). PD-1 is expressed on activated T cells, B cells, myeloid cells and on a subset of thymocytes. Ligation of PD-1 by PD-L1 (B7-H1; CD274) or PD-L2 (B7-DC; CD273) inhibits TCR-mediated T cell proliferation and production of IL-1, IL-4, IL-10 and IFN-gamma. In addition, PD-1 ligation also inhibits BCR mediated signaling. PD-1 deficient mice have a defect in peripheral tolerance and spontaneously develop autoimmune diseases. Soluble form of PD-1 (sPD-1) is expressed upon immune cells activation and can be secreted in the serum/plasma. Soluble checkpoints, such as sPD-1 or sPD-L1, are involved in positive or negative immune regulation and changes in their serum/plasma levels affect the development, prognosis and treatment of cancer. Increase of sPD-1 or sPD-L1 levels have been detected in patients with different types of cancer. This PD-1 (human) ELISA kit is developed to detect specifically sPD-1 (human) in different biological fluids.

靶标/特异性:

Detects soluble human PD-1 (sPD-1) in serum, plasma and cell culture supernatant.

保存温度:

+4°C

运输温度:

产地:

瑞士

灵敏度:

1.6pg/ml

检测范围:

3.125 to 200pg/ml

检测方法: