PD-L1 (human) ELISA Kit-人ELISA试剂盒-深圳欣博盛生物科技有限公司

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PD-L1 (human) ELISA Kit

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-45B-0016-KI01

规格：96 wells

目录价：￥7320

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PD-L1 (human) ELISA Kit

别名:

Programmed Cell Death 1 Ligand Protein 1; PDCD1 Ligand 1; B7-H1; PDL1; CD274

产品描述:

PD-L1 (also known as Programmed Cell Death 1 Ligand Protein 1; CD274 or B7-H1) is an immuno-coinhibitory member of the B7 family and functions as an immune checkpoint via its interaction with its receptors PD-1 (CD279) and CD80 (also known as B7-1). PD-L1 is expressed by hematopoietic cells such as T, B and dendritic cells and by parenchymal cells in response to cytokine (i.e. IFN-gamma) induction. Ligation of PD-1 by PD-L1 (B7-H1; CD274) or PD-L2 (B7-DC; CD273) inhibits TCR-mediated T cell proliferation and production of IL-1, IL-4, IL-10 and IFN-gamma and also inhibits BCR mediated signaling. PD-L1 binding to CD80 inhibits T cells proliferation. PD-1 deficient mice have a defect in peripheral tolerance and spontaneously develop autoimmune diseases. Soluble form of PD-L1 (sPD-L1) is expressed upon immune cells activation and can be secreted in the serum/plasma. Soluble checkpoints, such as sPD-1 or sPD-L1, are involved in positive or negative immune regulation and changes in their serum/plasma levels affect the development, prognosis and treatment of cancer. Increase of sPD-L1 or sPD-1 levels have been detected in patients with different types of cancer. This PD-L1 (human) ELISA kit is developed to detect specifically sPD-L1 (human) in different biological fluids.

靶标/特异性:

Detects soluble human PD-L1 (sPD-L1) in serum, plasma and cell culture supernatant.

保存温度:

+4°C

运输温度:

产地:

瑞士

灵敏度:

0.8pg/ml

检测范围:

2.34 to 150pg/ml

检测方法: