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折扣/货期| 货号：GTX14145 | 规格：500μg | 目录价：￥4700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PD-L1 antibody [10F.9G2]
反应种属:
Mouse
宿主来源:
Rat
实验应用:
FCM, ICC/IF, IHC-Fr, Neutralizing/Inhibition, WB
同种型:
IgG2b
免疫原:
Mouse CD274
克隆性:
Monoclonal
克隆号:
10F.9G2
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
预期分子量:
33
产品形式:
Liquid
存储溶液:
Filter-sterilized PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Mice deficient for this gene display a variety of phenotypes including decreased allogeneic fetal survival rates and severe experimental autoimmune encephalomyelitis. [provided by RefSeq, Sep 2015]
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