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折扣/货期| 货号：GTX52467 | 规格：50μg | 目录价：￥8000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PDGF beta antibody [5F66]
别名:
IBGC5 , PDGF2 , PDGFB , SIS , SSV , csis , platelet derived growth factor subunit B , PDGF-B
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P, WB
靶标/特异性:
This antibody shows approximately some degree (40%) cross-reactivity with PDGF-AB and no cross-reactivity with recombinant PDGF-AA.
同种型:
IgG1
免疫原:
Human PDGF B recombinant protein
克隆性:
Monoclonal
克隆号:
5F66
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
200 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
27
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
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