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折扣/货期| 货号：GTX42416 | 规格：50μg | 目录价：￥5400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PDGF Receptor beta antibody [PR7212]
别名:
platelet derived growth factor receptor beta , CD140B , IBGC4 , IMF1 , JTK12 , KOGS , PDGFR , PDGFR-1 , PDGFR1 , PENTT
反应种属:
Baboon, Golden Syrian Hamster, Human, Monkey
宿主来源:
Mouse
实验应用:
Depletion, FCM, ICC/IF, IHC-Fr, IHC-P, IP, WB
靶标/特异性:
This antibody is specific for human PDGF receptor beta protein, and it does not cross react with human PDGF receptor alpha protein.
同种型:
IgG1
免疫原:
Human skin fibroblast cell membrane extracts.
克隆性:
Monoclonal
克隆号:
PR7212
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
124
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
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