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折扣/货期| 货号：GTX01949 | 规格：500μl | 目录价：￥9600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Perforin antibody [5B10]
别名:
perforin 1 , HPLH2 , P1 , PFP
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
靶标/特异性:
This antibofy shows cross-reactivity with smooth muscle and differentiated epithelium.
同种型:
IgG1
免疫原:
Recombinant prokaryotic protein corresponding to an external region of the C-terminus of the perforin molecule.
克隆性:
Monoclonal
克隆号:
5B10
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Tissue culture supernatant, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
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