GABA A Receptor Alpha 5 Antibody: ATTO 488-单抗-深圳欣博盛生物科技有限公司

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GABA A Receptor Alpha 5 Antibody: ATTO 488

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SMC-494D-A488

规格：100 µg

目录价：￥4926.6

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

GABA A Receptor Alpha 5 Antibody: ATTO 488

别名:

Gamma-aminobutyric acid receptor subunit alpha-5 Antibody, GABA(A) Receptor subunit Alpha-5 Antibody, Gabra5 Antibody

产品描述:

Mouse Anti-Human GABA A Receptor Alpha5 Monoclonal IgG1

反应种属:

Human | Mouse | Rat

宿主来源:

Mouse

实验应用:

WB | IHC | ICC/IF

靶标/特异性:

Detects ~55kDa. Does not cross-react with GABA A Receptor Alpha2 or other GABA-A Receptors based on KO validation data.

同种型:

IgG1

推荐稀释度:

WB (1:1000); optimal dilutions for assays should be determined by the user.

免疫原:

Fusion protein amino acids 368-419 (last cytoplasmic domain before extracellular C-terminus) of human GABA A Receptor Alpha5.

免疫原种属:

Human

克隆性:

Monoclonal

克隆号:

N415/24 (Formerly sold as S415-24)

纯化方式:

Protein G Purified

偶联:

ATTO 488

产品浓度:

1 mg/ml

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS pH7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

The GABA A Receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2). Recent research shows their usage in investigating side effects of drugs and the effects of learning and memory. Inverse agonists of the Alpha5 subunit may be useful in the treatment of Alzheimer's Disease (3).

Accession #:

NP_000801.1