深圳欣博盛生物科技有限公司 a1

Phospholamban antibody
货号:GTX37204 规格:100μg 目录价:¥8200
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Phospholamban antibody
别名:
phospholamban , CMD1P , CMH18 , PLB
反应种属:
Rat
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
A synthetic peptide corresponding to a sequence at the N-terminus of human PLN(2-16aa EKVQYLTRSAIRRAS), identical to the related rat and mouse sequences.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
6
产品形式:
Liquid
存储溶液:
0.001% Na₂HPO₄, 0.0045% NaCl, 0.025% BSA, 0.00025% Thimerosal, 0.00025% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy. [provided by RefSeq, Apr 2016]
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