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折扣/货期| 货号：SMC-188D-APC | 规格：100 µg | 目录价：￥4825.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Piccolo Antibody: APC
别名:
ACZ Antibody, Aczonin Antibody, PCLO Antibody, Pico Antibody, presynaptic cytomatrix protein Antibody
产品描述:
Mouse Anti-Human Piccolo Monoclonal IgG2b Kappa
反应种属:
Human | Mouse | Rat
宿主来源:
Mouse
实验应用:
WB | ICC/IF | ELISA
靶标/特异性:
Detects ~550kDa. No cross-reactivity to Bassoon.
同种型:
IgG2b Kappa
推荐稀释度:
WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
免疫原:
Human full length recombinant protein (GenBank ID: BC001304.1)
免疫原种属:
Human
克隆性:
Monoclonal
克隆号:
6H9-B6
纯化方式:
Protein G Purified
偶联:
APC
产品浓度:
1 mg/ml
保存温度:
Conjugated antibodies should be stored according to the product label
运输温度:
Blue Ice or 4ºC
存储溶液:
PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
产地:
加拿大
功能与背景:
Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains (1, 2). In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) (3). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1 (2).
Accession #:
NP_001104266.1
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