| 货号:GTX53794 | 规格:100μl | 目录价:¥5300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PIG3 antibody [AT1C9]
别名:
tumor protein p53 inducible protein 3 , PIG3
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, WB
同种型:
IgG2a
免疫原:
Recombinant human PIG3 (1-332aa) purified from E. coli
克隆性:
Monoclonal
克隆号:
AT1C9
纯化方式:
By protein-G affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
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