PIM2 antibody [10A12]-单抗-深圳欣博盛生物科技有限公司

首页产品中心单抗

PIM2 antibody [10A12]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX83886

规格：100μl

目录价：￥7300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PIM2 antibody [10A12]

别名:

Pim-2 proto-oncogene, serine/threonine kinase

反应种属:

Dog, Human, Monkey, Rat

宿主来源:

Mouse

实验应用:

FCM, IHC-P, WB

同种型:

IgG2a

免疫原:

Full length human recombinant protein of human PIM2 (NP_006866) produced in HEK293T cell.

克隆性:

Monoclonal

克隆号:

10A12

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

0.84 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

Promotes cell survival in response to a variety of proliferative signals via positive regulation of the I-kappaB kinase/NF-kappaB cascade | this process requires phosphorylation of MAP3K8/COT. Prevents apoptosis induced by growth factor withdrawal via inhibition of caspase-3 activation, and via phosphorylation of pro-apoptotic proteins. Inhibits BAD-induced cell death via phosphorylation of BAD. PIM2-mediated cell survival is glucose-dependent but independent of several AKT regulators such as PI3K, HSP-90 and TOR, indicating that PIM2 and PI3K/AKT/TOR function via distinct pathways. Involved in the positive regulation of chondrocyte survival and autophagy in the epiphyseal growth plate.

您可能感兴趣的产品

4-Hydroxy Nonenal [HNEJ-1] Monoclonal Antibody (Clone IG10) - Biotinylated

货号：45026

PD-1/CD279 Recombinant Monoclonal Antibody (Clone Pembrolizumab)

货号：45002

Sulfatide Recombinant Monoclonal Antibody (Clone GAMEG3)

货号：44723

Mertansine Monoclonal Antibody (Clone 2D12)

货号：44707

MMAE Monoclonal Antibody (Clone 1G1)

货号：44706

Microsomal Epoxide Hydrolase Monoclonal Antibody (Clone 1H9)