PKC eta (phospho Thr655) antibody-多抗-深圳欣博盛生物科技有限公司

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PKC eta (phospho Thr655) antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX25798

规格：50μl

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PKC eta (phospho Thr655) antibody

别名:

protein kinase C eta , PKC-L , PKCL , PRKCL , nPKC-eta

反应种属:

Human

宿主来源:

Rabbit

实验应用:

FCM, WB

靶标/特异性:

This antibody does not cross-react with any other PKC isoforms tested.

同种型:

IgG

免疫原:

The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human PKC-eta that contains threonine 655.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified IgG

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.1% BSA, 0.05% Sodium azide.

生产商:

GeneTex

功能与背景:

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. Mutations in this gene are associated with susceptibility to cerebral infarction. [provided by RefSeq, Sep 2015]

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