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折扣/货期| 货号：GTX38559 | 规格：50μl | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PLCG2 (phospho Tyr753) antibody
别名:
phospholipase C gamma 2 , APLAID , FCAS3 , PLC-IV , PLC-gamma-2
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ICC/IF, WB
靶标/特异性:
This antibody detects endogenous levels of PLC gamma 2 only when phosphorylated at tyrosine 753.
同种型:
IgG
免疫原:
The antiserum was produced against synthesized phosphopeptide derived from human PLC gamma 2 around the phosphorylation site of tyrosine 753 (S -L-Y(p)-D-V).
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
148
产品形式:
Liquid
存储溶液:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
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