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折扣/货期| 货号：GTX22825 | 规格：100μl | 目录价：￥5600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PMCA ATPase antibody [5F10]
别名:
ATPase plasma membrane Ca2+ transporting 1 , PMCA1 , PMCA1kb
反应种属:
Amphibians, Bovine, Cat, Chicken, Dog, Hamster, Human, Mouse, Pig, Primate, Rabbit, Rat, Sheep
宿主来源:
Mouse
实验应用:
FCM, ICC/IF, IHC-Fr, IHC-P, IP, Neutralizing /Inhibition, WB
靶标/特异性:
This antibody detects all four known isoforms of the PMCA ATPase. This antibody recognizes an epitope between amino acids 724-783 of the human erythrocyte calcium pump.
同种型:
IgG2a
免疫原:
Purified human erythrocyte calcium ATPase.
克隆性:
Monoclonal
克隆号:
5F10
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Ascites, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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