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折扣/货期| 货号：GTX23529 | 规格：100μg | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PMCA2 ATPase antibody
别名:
ATPase plasma membrane Ca2+ transporting 2 , PMCA2 , PMCA2a , PMCA2i
反应种属:
Chicken, Human, Mouse, Pig, Rat
宿主来源:
Rabbit
实验应用:
ELISA, ICC/IF, IHC-Fr, IHC-P, IP, WB
靶标/特异性:
This antibody detects an ~127 kDa protein and an ~133 kDa protein representing PMCA2a and PMCA2b ATPase, respectively, from rat brain microsomal fractions.
同种型:
IgG
免疫原:
Synthetic Peptide: T(5) N S D F Y S K N Q R N E S S(19)
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
137
产品形式:
Liquid
存储溶液:
PBS, 0.1% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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